Follistatin ELISA Kit is a glycosylated single-chain protein that is expressed in a wide variety of tissues.
Following the discovery of the Inhibins and Activins, Follistatin was initially isolated from bovine and porcine follicular fluid in 1987 after the discovery that an Inhibin-like substance in these follicular fluids was able to modulate FSH production by pituitary cells in culture . Diagnostic Systems Laboratories, Inc. Activin stimulates pituitary FSH secretion whereas Inhibin and Follistatin are inhibitory.
Shortly after its discovery, Follistatin was shown to be a potent activin-binding protein which acts by neutralizing the actions of the Activins. The activin-follistatin binding complex is generally considered to be composed of one activin and two Follistatin molecules, and the affinity of binding between Follistatin and activin is similar to that of activin for its receptor.
Specification: 96Test
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Following the discovery of the Inhibins and Activins,
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