What is PVB19 IgM ELISA Kit?

BACKGROUND: Infections with parvovirus B19 (PVB19) can cause significant morbidity in transplant recipients.
METHODS: To characterize the epidemiology and clinical spectrum of posttransplant PVB19 IgM ELISA Kit, we reviewed all cases at our institution during a 16-year period, summarized the data from 91 cases published in the medical literature, and performed longitudinal molecular surveillance for PVB19 DNAemia among 47 solid organ and hematopoietic stem cell transplant recipients.
RESULTS: The median time to onset of PVB19 disease was 7 weeks after transplantation. Anemia, leukopenia, and thrombocytopenia were present in 98.8%, 37.5%, and 21.0% of patients, respectively. Hepatitis, myocarditis, and pneumonitis were also reported in association with PVB19 disease. Allograft tissue loss or dysfunction was observed at the time of PVB19 disease in 10% of cases. At the onset of disease, PVB19 IgM ELISA Kit serological test results were negative in 29% of cases. Almost all patients (96%) with anti-PVB19 IgM had a positive PVB19 polymerase chain reaction assay result. Intravenous immunoglobulin was the most commonly used treatment modality. Three of 98 patients died of myocarditis and cardiogenic shock associated with PVB19 disease. Molecular surveillance throughout the first year after transplantation did not reveal PVB19 DNAemia in 47 anemic solid organ and hematopoietic stem cell transplant patients.
PVB19 is a rare but clinically significant infection that manifests as refractory anemia during the posttransplantation period. The use of polymerase chain reaction for diagnosis is particularly helpful in immunosuppressed transplant patients who may fail to mount antibodies against PVB19 during active infection.
More about: PVB19 IgM ELISA Kit sale
Read more: Reagent Product

What is sPLA2 ELISA Kit?

Intended use of sPLA2 ELISA Kit
This immunoassay kit allows for the specific measurement of human secreted phospholipase A2, sPLA2 concentrations in cell culture supernates, serum and plasma.
Introduction
Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position yielding a free fatty acid and a lysophospholipid. The release of arachidonic acid from membrane phospholipids by PLA2 is believed to be a key step in the control of eicosanoid production within the cell.
Test principle
sPLA2 ELISA Kit employs the quantitative sandwich enzyme immunoassay technique. A antibody specific for sPLA2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any sPLA2 present is bound by the immobilized antibody. An enzyme-linked antibody specific for sPLA2 is added to the wells. Following a wash to remove any unbound antibody-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of sPLA2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Description
This kit contains materials with small quantities of sodium azide. Sodium azide reacts with lead and copper plumbing to form explosive metal azides. Upon disposal, flush drains with a large volume of water to prevent azide accumulation. Avoid ingestion and contact with eyes, skin and mucous membranes. In case of contact, rinse affected area with plenty of water. Observe all federal, state and local regulations for disposal. 
All blood components and biological materials should be handled as potentially hazardous. Follow universal precautions as established by the Centers for Disease Control and Prevention and by the Occupational Safety and Health Administration when handling and disposing of infectious agents.
More about: sPLA2 ELISA Kit sale
Read more: Elisa kits

Description of Anti--HCMV PP65/HHV5 PP65(Human Cytomegalovirus PP65)

Anti--HCMV PP65/HHV5 PP65(Human Cytomegalovirus PP65)
Synonym: CMV, CMV glycoprotein B, CMV glycoprotein GP55, Cytomegalovirus glycoprotein GP55, gB, Glycoprotein B, Glycoprotein GP55, HCMV, HCMV glycoprotein B, HCMV glycoprotein GP55, HHV 5, HHV 5 glycoprotein B, HHV 5 glycoprotein GP55, HHV5 glycoprotein B, HHV5 glycoprotein GP55, Human herpesvirus 5 glycoprotein B, Human herpesvirus 5 glycoprotein GP55, UL55.
Description of Anti--HCMV PP65/HHV5 PP65(Human Cytomegalovirus PP65)
Cytomegalovirus is a herpes viral genus of the Herpesviruses group: in humans it is commonly known as HCMV or Human Herpesvirus 5 (HHV-5).CMV belongs to the Betaherpesvirinae subfamily of Herpesviridae, which also includes Roseolovirus.
 HCMV is also the virus most frequently transmitted to a developing fetus. HCMV infection is more widespread in developing countries and in communities with lower socioeconomic status and represents the most significant viral cause of birth defects in industrialized countries. CMV "seems to have a large impact on immune parameters in later life and may contribute to increased morbidity and eventual mortality.
More about: Anti--HCMV PP65/HHV5 PP65(Human Cytomegalovirus PP65) sale
Read more: Reagent Product

Specifications of Follistatin ELISA Kit

Follistatin ELISA Kit
Tests: 1 x 96 well plate
Sample type
Cell culture supernatant, Urine, Serum, Plasma
Assay type: Sandwich
Sensitivity: < 0.5 ng/ml
Range: 0.512 ng/ml - 125 ng/ml
Recovery: 90%
Synonyms: CG12955, CG12956, Fol1, dFS, dFol1, Dmel\CG33466, CG33466, FS, xfs, MGC79635, FST, fst, LOC100033825, Fst, AL033346, FOL1, Fst-288, RATFOL1
Follistatin ELISA Kit(Enzyme-Linked Immunosorbent Assay) is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Follistatin in serum, plasma, cell culture supernatants and urine. This assay employs an antibody specific for human Follistatin coated on a 96-well plate. Standards and samples are pipetted into the wells and Follistatin present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-human Follistatin antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of Follistatin bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Storage    
May be stored for up to 6 months at 2° to 8°C from the date of shipment. Standard (recombinant protein) should be stored at -20°C or -80°C (recommended at -80°C) after reconstitution. Opened Microplate Wells or reagents may be stored for up to 1 month at 2° to 8°C. Return unused wells to the pouch containing desiccant pack, reseal along entire edge. Note: the kit can be used within one year if the whole kit is stored at -20°C . Avoid repeated freeze-thaw cycles.
More about: Follistatin ELISA Kit sale
Read more: Reagent Product

Where to buy Anti-SAP-1/FRG4(Synapse associated protein- I)?

Description:
SAP-1 is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases.
SAP1 is a negative regulator of integrin-mediated signalling and has been implicated in carcinogenesis in many cancer types including gastro-intestinal and heptocellular cancers.
SAP-1 is a transmembrane protein and its gene is expressed primarily in brain and liver, and at a lower level in heart and stomach. It is also expressed in several cancer cell lines, but not in the corresponding normal tissues.
More about: Anti-SAP-1/FRG4(Synapse associated protein- I) sale
Read more: Elisa kits

Descriptions of BDNF ELISA Kit

Descriptions of BDNF ELISA Kit
Tests: 1 x 96 well plate
Sample type
Cell culture supernatant, Urine, Serum, Plasma
Assay type: Sandwich
Sensitivity: < 80 pg/ml
BDNF ELISA Kit is found in neurons of the central nervous system. It is expressed predominantly in hippocampus, cortex, and synapses of the basal forebrain. BDNF selectively supports the survival of primary sensory neurons and retinal ganglia. It supports survival and differentiation of certain cholinergic neurons and also some dopaminergic neurons in vitro. The factor inhibits the normal cell death of embryonic chick motor neurons.
The ab99978 Human BDNF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human BDNF in serum, plasma, cell culture supernatants and urine. This assay employs an antibody specific for human BDNF coated on a 96-well plate. Standards and samples are pipetted into the wells and BDNF present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated antihuman BDNF antibody is added.
More about: BDNF ELISA Kit sale
Read more: Elisa kits

Are you buying Troponin-T ELISA kit?

Troponin is a complex of three regulatory proteins that is integral to muscle contraction in skeletal and cardiac muscle, but not smooth muscle. Troponin is attached to the protein tropomyosin and lies within the groove between actin filaments in muscle tissue. Troponin is a component of thin filaments (along with actin and tropomyosin), and is the protein to which calcium binds to accomplish this regulation. Troponin has three subunits, Troponin C, Troponin I, and Troponin T. Individual subunits serve different functions. Troponin C binds to calcium ions to produce a conformational change in TnI. Troponin T binds to tropomyosin, interlocking them to form a troponin-tropomyosin complex. And in a less complicated light, Troponin T modulates contraction of striated muscle. Troponin I binds to actin in thin myofilaments to hold the troponin-tropomyosin complex in place.
Intended use
This immunoassay kit allows for the in vitro quantitative determination of mouse Troponin T, Tn-T concentrations in serum, plasma and other biological fluids.
More about: Troponin-T ELISA kit sale
Read more: Elisa assay kits

What is Tag antibody?

Description of Tag antibody
An epitope is an antigenic determinant, a biological structure or sequence to which an antibody binds. Recombinant DNA technology allows us to construct fusion proteins which each expressed from gene of interest and consists an epitope tag. These fusion proteins can be identified and purified by using epitope tag specific antibodies, which simplifies the time-consuming and labor-intensive task of antibody generation from already complicated process. The most commonly used epitope tags include His tag (6-Histidine), HA tag (Hemagglutinin), c-Myc tag, GST tag, and DYKDDDDK.
More about: Tag antibody sale
Read more: Elisa assay kits

Anti-ISR（Insulin Receptor）

Anti-ISR（Insulin Receptor） is a heterotetrameric membrane glycoprotein with tyrosine-protein kinase activity, consisting of disulfide-linked subunits in a beta-alpha-alpha-beta configuration. The beta subunit possesses a single transmembrane domain, whereas the alpha subunit is completely extracellular. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Binding of insulin to the insulin receptor stimulates its association with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K) which leads to glucose uptake. Two transcript variants encoding different isoforms have been found for this gene produced by alternative splicing.
More about: Anti-ISR（Insulin Receptor） sale
Read more: Elisa assay kits

Where to buy BD-2 ELISA Kit?

Synonyms: BD-2, hBD-2, Defensin beta 2, Skin-antimicrobial peptide 1, SAP1, DEFB4, DEFB102, DEFB2, DEFB4P, Beta-defensin 2
Standard Curve Range
8-1000 pg/ml
Storage
1 year at 2-8°C
Sample Type
Serum, Plasma, Supernatants from cell cultures
BD-2 ELISA Kit contains all the necessary reagents required for performing quantitative measurement of Human BD-2 levels from samples including serum, plasma, culture medium or other biological fluids in a sandwich ELISA format.
BD-2 ELISA Kit contains the key components required for the quantitative measurement of natural and/or recombinant hBD-2?in a sandwich ELISA format within the range of 8- 1000pg/ml. Using the ELISA protocol described below, the recommended microplates, reagents and solutions, the components supplied in this kit are sufficient to assay Human BD-2 ?in approximately 1000 ELISA plate wells.
More about: BD-2 ELISA Kit sale
Read more: Elisa assay kits

What is Mumps IgA ELISA kit?

Intended Use
Mumps IgA ELISA kit has been designed for the the detection and thequantitative determination of specific IgA antibodies against Mumps virus inserum and plasma. Further applications in other body fluids are possible andcan be requested from the Technical Service. This assay is intended forin-vitro diagnostic use only. Laboratory results can never be the only baseof a medical report. The patient history and further tests have additionallyto be taken into account.
General Information of Mumps IgA ELISA kit
Mumps(Parotitis) is a common contagious disease with relatively moderate symptomsduring childhood, but increasing complications, when adults are infected. Thecausative agent of mumps is a virus of the Paramyxoviridae family. The virusnormally infects children at the age of 4 to 10. The infection is mainlytransmitted by the airborne route, but is also spread by various objectscontaminated by the patient saliva. The disease shows a seasonal prevalencewith the greatest incidence in winter and spring. Both a mumps infection orvaccination lead to a persistent immunity. The typical symptom associatedwith a mumps infection is a „parotitis“ (swelling of the parotid glands).Additionally pathological involvement of the CNS and various glandular organs(pancreas, thymus, thyroids) is a typical feature of mumps. A mumps inducedmeningitis is one of the most frequent manifestations of the disease whichcan also appear without parotitis. The published data about the presence ofmeningitis vary between 1.4% and 66% of the clinically ill patients. In most casesthere follows reconvalescence without complications. The recognition of Mumpsin the laboratory is mostly done by detection of the infectious agent itselfor by the determination of virus-specific antibodies. The serodiagnosis playsa major part. Besides the classical methods like complement fixation, hemagglutinationand neutralisation tests have been introduced a series of modern assays likeimmunofluorescence, radio immunoassay and enzyme immunoassay. The immunity ofan individual is monitored by an IgG ELISA. Increasing IgG titers are helpfulin the determination of the causative agent because cross reactions with Parainfluenza-Virustype 2 may lead to a wrong interpretation of the patient reports. In theearly stage of the disease, significant IgM titers may be monitored.
More about: Mumps IgA ELISA kit sale
Read more: Elisa assay kits

Description of Microalbumin ELISA kit

Microalbumin ELISA kit - For the quantitative determination of albumin in human Urine. Sample Types: Urine. Sample Size: 10 μl. Range: 0.5 - 100 μg/ml. Sensitivity: 0.24 μg/ml. Incubation Time: 40 minutes(s)
Description:
Under normal physiological conditions very little albumin is present in the urine. Approximately 99% of the filtered albumin is reabsorbed in the proximal tubule. In pathologic conditions when glomerular capillary wall permeability and/or filtration rate increase, albumin excretion along with other macromolecules in urine also increases. On the other hand, when proximal tubular reabsorptive capacity decreases, excretion of smaller macromolecules such as beta 2 micro globulin and lysozyme in urine increases. Thus, determining the clearance ratio of urinary albumin to beta 2 micro globulin can help localize the site of renal impairment.
Detection of increased urinary albumin excretion is of particular importance in the early diagnosis of incipient renal disease. Thus, a sensitive method of measuring minor increase in urinary albumin is of great significance to a) detect minimal renal impairment and b) to control its progression in developing end stage renal disease and cardiovascular disease amongst diabetics. A recent consensus report by Centers for Disease Control and the National Institute of Diabetes and Digestive and Kidney diseases recommend that albumin in the urine amongst diabetics be routinely monitored. Although the microalbuminuria is tested primarily in diabetes mellitus, it has also been used in studies of hypertension, pregnancy (pre-eclamsio, maternal morbidity and fetal mortality) non-diabetic renal disease and the renal effects of various drugs, hormones, and nephrotoxins.
More about: Microalbumin ELISA kit
Read more: Elisa assay kits

Where to buy Excitatory amino acid transporters 1?

Excitatory amino acid transporters 1 (EAATs), also known as glutamate transporters, belong to the family of neurotransmitter transporters. Glutamate is the principal excitatory neurotransmitter in the vertebrate brain. EAATs serve to terminate the excitatory signal by removal (uptake) of glutamate from the neuronal synapse into neuroglia and neurons.
Excitatory amino acid transporters 1 is membrane-bound secondary transporters that superficially resemble ion channels. These transporters play the important role of regulating concentrations of glutamate in the extracellular space by transporting it along with other ions across cellular membranes. After glutamate is released as the result of an action potential, glutamate transporters quickly remove it from the extracellular space to keep its levels low, thereby terminating the synaptic transmission.
Glutamate transporters also transport aspartate and are present in virtually all peripheral tissues including bone, heart, liver, and testes. They exhibit stereoselectivity for L-glutamate but transport both L- and D-aspartate.
More about: Excitatory amino acid transporters 1
Read more: Elisa kits

What is Chagas ELISA Kit?

Chagas disease occurs in Central and South America. It is an infectious disease transmitted to humans by the bite of an infected wound caused by errors of the family Reduviidae. The infection is caused by Trypanosoma cruzi causes a single-celled parasites.
The Test is for the qualitative determination of serum antibodies in humans, primarily IgG, to Trypanosoma cruzi using the ELISA technique.
Trypanosoma cruzi is a protozoan parasite, which is the causative agent of Chagas’ disease. This disease ranges from southern United States to Northern Argentina and Chile. The disease is transmitted to humans through the bite wound caused by reduviid bugs, blood transfusions, and in newborns, infection in utero. In acute infections, there may be few or no symptoms of the disease. In chronic infections, there may be inflammatory cardiomyopathy, or severe dilation of the esophagus or colon known as megadisease.
More about: Chagas ELISA Kit
Read more: Elisa kits

How to get Anti-Lgr5/GPR49?

Lgr5 (Leucine-rich repeat G protein-coupled receptor 5) is thought of as a possible stem cell marker for the hair follicle and the epithelium of the intestine. LGR5 is only expressed in cycling crypt base columnar cells, which are thought to be genuine intestinal stem cells. LGR5 has also been implicated as a negative regulator of the Wnt signaling pathway. Lgr5 is often up-regulated in certain cancers and may play a role in cancer cell progression.
Specificity:
This antibody recognizes LRG5 at the cytoplasmic domain.
More about: Anti-Lgr5/GPR49 sale
Read more: Elisa kits

What is Poliomyelitis IgG ELISA kit?

Description: Enzyme immunoassay for the detection of human IgG antibodies against Poliomyelitis Virus in serum and plasma.
Introduction: Poliomyelitis IgG ELISA kit is an infection caused by enterovirus, which occurs epidemically world-wide, and which often leads to paralysis and death. Three types of human-pathogenic poliomyelitis viruses are actually known:
Polioviruses mainly proliferate in the lymph nodes of the intestine, and are excreted via feces. The throat can also be infected, and the viruses then leave the body orally. After the infection, the viruses are distributed via monocytes into other lymph nodes, where they multiplicate. In a second viremic phase they settle in the whole organism, amongst others in the central nervous system. In more than 90% of the infections the patient does not suffer any subjective symptoms. In the remaining other cases there appear: unspecific illness with slight fever, head and throat irritations, diarrhoea, nausea, and vomiting. Very rarely the classical paralysis with affliction of muscles and cerebral nerves is seen. The reconvalescent phase can last up to two years, frequently there stay long-lasting damages.
Intended Use: The Polio IgG Antibody ELISA Test Kit has been designed for the detection of IgG class antibodies against Polio in serum and plasma.
More about: Buy Poliomyelitis IgG ELISA kit
Read more: Elisa kits

The Application of CCP Peptide ELISA kit

Cyclic citrullinated peptide is also recognised since "CCP". It embodies a cyclic peptide incorporating the amino acid citrulline.citrulline is incorporated enzymatically into proteins, what is called citrullination.      Small volumes of CCP elisa kit may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. Recently, these ACPAs have turned up as powerful biomarkers, which are accepted as a major diagnostic instrument inward diagnosing rheumatism (RA) already in a very early stage of disease.

anti-CCP; Buy CCP elisa kit :: cyclic cirtullinated peptide, ELISA Kit (MBS720363) datasheet at MyBioSource; anti-CCP; CCP; anti-cyclic cirtullinated peptide; Human Anti-cyclic cirtullinated peptide ELISA Kit; Human Anti-cyclic cirtullinated peptide ELISA Kit; Anti-cyclic cirtullinated peptide; Anti-cyclic cirtullinated peptide (Human); Ccp Human . (NCBI/UniProt 226941355 YP_002796429.1); Human ELISA Kit; NC_012559.1 (2330366..2330938); 7758049; CCP elisa kit; anti-CCP

The anti-CCP test comes in a 96-well microtiter plate strip-well format that employs a second-generation peptide antigen. The kit features five calibrators, three controls, and a color-coded, liquid-stable staining system. The assay is performed in about 2 minutes at room temperature and can employment serum or plasma. Additionally, the kit has an 18-month shelf life and an open-kit stability of 3 months when refrigerated.

More about: CCP Peptide ELISA kit

Read more>> Elisa assay kits

The Functions of Anti-CXC-R3

Chemokine receptor CXCR3 is a Gαi protein-coupled receptor in the CXC chemokine receptor family. Other names for CXCR3 are G protein-coupled receptor 9 (GPR9) and CD183.

CXCR3 is able to regulate leukocyte trafficking.

CXCR3 is a receptor for CXCL9, CXCL10 and CXCL11 and mediates the proliferation of human mesangial cells (HumanC). Isoform 2 is a receptor for CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the growth of human microvascular endothelial cells (HumanVEC).

synthetic peptide corresponding to the C-terminus of human CXC chemokine receptor 3 (CXCR3), conjugated to KLH. The immunizing peptide has 82% homology with the rat and mouse gene.

Neutralization (ND50): ~0.3-1.5ug/ml in the presence of 7ng/ml of Recombinant human CXCL11/l-TAC, using the hCXCR3 transfected BaF/3 cells in a chemotaxis assay.  Isoform 2 may play a role in angiogenesis. Isoform 3 mediates activity of CXCL11. Binding of chemokines to CXCR3 induces various cellular responses, most notably integrin activation, cytoskeletal changes and chemotactic migration. CXCR3-ligand interaction attracts Th1 cells and promotes Th1 cell maturation. Mouse myeloma with B cells obtained from a mouse inoculated with human CXCR3 transfected NS0 mouse myeloma cells.

More about:  Anti-CXC-R3/CD183

Read more>> Elisa assay kits

The Functions of Anti-P-p38 ERK/MAPK14

The protein encoded by Anti-P-p38 ERK/MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, recording regularization and exploitation.

Specific combination antigen: antibody itself cannot direct dissolve or killer with a specific antigen to target cells, usually need to complement or phagocytic cells together to clear the effect of pathogenic microorganisms or lead to pathological damage. However, with the virus antibodies can be or poison the specificity of the union, and the role of the virus directly play.

This kinase equals sparked off by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase.

The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cellular telephone cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four as an alternative spliced transcript discrepancies of this gene cyphering distinguishable isoforms have been reported.

More information: Anti-P-p38 ERK/MAPK14

Read more>> Elisa assay kits

The New Application of Serotonin ELISA

Serotonin ELISA is an elisa for the in-vitro diagnostic quantitative determination of serotonin inwards human being blood serum, plasma, platelets and urine. Further the test can be used for research of tissue homogenates and cell culture supernatants.Serotonin is an intermediate product of tryptophan metabolism and is located primarily in the enterochromaffin cells of intestine, serotonergic neurons from the brain, platelets of the blood and is well established as a neurotransmitter in the central nervous system.

Intimately totally of the serotonin in disseminating origin is concentrated in platelets. Interpolated densenesses of circularizing serotonin have been implicated in several pathological conditions including chronic tension concern, schizophrenic disorder, hypertension, Huntington′sec disease, Duchenne′randomness muscular dystrophy and early acute appendicitis. Enzyme immunoassay for the in-vitro diagnostic quantitative determination of Serotonin in human serum, plasma, platelets, urine. Boost the examine could cost used for research of tissue homogenates and cell culture supernatants.

The determination of serum serotonin floors equals of heights nonsubjective import for symptomatic assessment of carcinoid syndrome. An increasing interest in the determination of serotonin in platelets including uptake and release kinetics is gestated in the near ulterior.

More information: Serotonin ELISA

Read more>> Elisa assay kits

The New Information about Collagen-Type-I ELISA

Collagen Type I (CI) is the most abundant protein and is found in the skin, connective tissue, tendons, ligaments, cornea, invertebral discs and bone. It is encoded by the genes COL1A1 and COL1A2 and is formed inside (along the rough endoplasmic reticulum) and outside (by procollagen peptidase and bound by fibronectin and integrin) the cell. Individual collagen molecules are cross-linked to one another within these fibrils.Type I collagen is the just about abundant conformation of collagen fashionable the individual consistency and is synthesized mainly by fibroblasts, osteoblasts, odontoblasts and chondroblasts. It is located in the extracellular matrix of many tissues of the body including cartilage, bone, tendon, skin and the sclera of the eye. This kit makes up organised to quantify collagen in various sources such as cell media, ECM (Extra Cellular Matrix) of civilization cellular telephone and tissue because the kit detects atelo-collagen which is prepared by pepsin digestion. Sensitivity : 0.02ug/ml, Range: 0.02-40ug/ml.

Type I collagen is composed of two pro-α1(I) chains, produced from the COL1A1 gene, and one pro-α2(I) chain, produced from the COL1A2 gene. Mutations in the genes that produce collagen type I are responsible for causing several health preconditions including Ehlers-Danlos syndrome, osteogenesis imperfecta, osteoporosis and Caffey disease. The formation of cross-links results in very strong type I collagen fibrils, which are discovered successful the spaces around cells.

Collagen Type I is involved in many human diseases such as fibrosis, osteoporosis, cancer and atherosclerosis.

More about:  Collagen-Type-I ELISA

Read more>> Elisa assay kits