Troponin is a complex of three regulatory proteins that is integral to muscle contraction in skeletal and cardiac muscle, but not smooth muscle. Troponin is attached to the protein tropomyosin and lies within the groove between actin filaments in muscle tissue. Troponin is a component of thin filaments (along with actin and tropomyosin), and is the protein to which calcium binds to accomplish this regulation. Troponin has three subunits, Troponin C, Troponin I, and Troponin T. Individual subunits serve different functions. Troponin C binds to calcium ions to produce a conformational change in TnI. Troponin T binds to tropomyosin, interlocking them to form a troponin-tropomyosin complex. And in a less complicated light, Troponin T modulates contraction of striated muscle. Troponin I binds to actin in thin myofilaments to hold the troponin-tropomyosin complex in place.
Intended use
This immunoassay kit allows for the in vitro quantitative determination of mouse Troponin T, Tn-T concentrations in serum, plasma and other biological fluids.
More about: Troponin-T ELISA kit sale
Read more: Elisa assay kits
No comments:
Post a Comment