Anti-5-HT(5-hydroxytryptamine) is directed adjoin conjugated anti-Serotonin antibodies. Anti-idiotypic antibodies are developed to mimick the physiological action of biomolecules.
Serotonin or 5-HT(5-hydroxytryptamine) is a monoamine neurotransmitter, biochemically acquired from tryptophan, that is primarily begin in the gastrointestinal (GI) tract, platelets, and axial afraid arrangement (CNS) of bodies and animals. It is a acclaimed contributor to animosity of well-being.
Serotonin is eventually metabolized to 5-HIAA by the liver, and excreted by the kidneys. One blazon of tumor, alleged carcinoid, sometimes secretes ample amounts of serotonin into the blood, which causes assorted forms of the carcinoid affection of flushing, diarrhea, and affection problems. Because of serotonin's advance announcement aftereffect on cardiac myocytes, bodies with serotonin-secreting carcinoid may ache a appropriate affection (tricuspid) valve ache syndrome, acquired by admeasurement of myocytes assimilate the valve.
Applications ELISA, Immunohistochemistry (IHC)
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